Clinical Trial Nexus

Clinical Trial Nexus is a bespoke evidence synthesis service that conducts systematic retrieval, harmonisation, and structuring of global clinical trial registry data on behalf of our clients. Using validated data extraction protocols and expert curation, we deliver project-based evidence mapping across indications, treatment settings, outcomes, and sponsor activity, designed to support early-stage research and strategic decision-making.

Clinical trial registry records vary widely in terminology, structure, and completeness – making systematic evidence retrieval and synthesis across treatment lines, sponsors, and outcomes time-consuming and error-prone. As trial volumes grow, traditional manual approaches no longer scale for research needs.

OUR METHODOLOGY

Clinical Trial Nexus conducts systematic retrieval and harmonisation of global clinical trial registry data for each client project, extracting and standardising key attributes such as indication, line of therapy, outcomes, sites and sponsors. Through expert-curated normalisation and quality-controlled workflows, each deliverable is a standalone research product – ready for exploratory analysis, evidence mapping, and internal strategic
planning.

  • Choon-Quinones, M., Obeng, G. D., Asiedu-Ayeh, B., Kawuo, S., Tukur, A. M., Mohammed, I., Obeng, A.P., Harousseau, J-L., Seckinger, A., Hose, D., Sarkodie, E., Imre, A., Csanádi, M. (2026). Increasing Trends of Minimal Residual Disease Measurement in Trials Focusing on Multiple Myeloma Treatment: A Systematic Analysis of Clinical Research Design From 2014 to 2025. European Journal of Haematology. Doi: 10.1111/ejh.70133
  • Puga, L., Cases Escute, M., Imre, A., Giles, R., Piggin, M., Leto di Priolo, S., Racovita, M., Ruth Wogu, L., Geissler, J., Hosszú, D., Józwiak, Á., Ágh, T., Pitter, J., Plate, A. (2025). 2309P European atlas on clinical trials in cancer and haematology (EuroACT): Mapping research and equity across Europe. Annals of Oncology. Doi:10.1016/j.annonc.2025.08.2925
  • Cases, M., Imre, A., Giles, R. H., Puga, L., Piggin, M., Geissler, J., Racovita, M., Leto di Priolo, S., Wogu, L. R., Hyseni-Bocolli, A., Morgan, K., Hosszú, D., Józwiák, Á., Ágh, T., Plate, A. & EuroACT Working Group (2025). Geographic Inequities in Patient-Reported Outcome Measures in Clinical Trials of Selected Solid Tumours in Europe: Findings from EuroACT. Available at SSRN:  http://dx.doi.org/10.2139/ssrn.5390471
  • Cases, M., Imre, A., Giles, R. H., Puga, L., Piggin, M., Geissler, J., Racovita, M., Leto di Priolo, S., Wogu, L. R., Hyseni-Bocolli, A., Morgan, K., Hosszú, D., Pitter, J. G., Ágh, T., Plate, A. (2025).  Variation in Use of Patient-Reported Outcome Measures and in Geographical Distribution in Clinical Trials of Selected Malignant and Non-Malignant Haematological Diseases in Europe: Findings from EuroACT. Available at SSRN:  http://dx.doi.org/10.2139/ssrn.5646744

SYREON RESEARCH INSTITUTE OFFERS

  • Structured Analysis and Visualisation
  • Line-of-Therapy Intelligence
  • Publication Mapping
  • Comprehensive Multi-registry Coverage

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